Meta-Analysis of Pain Management in Epidermolysis Bullosa

Pain is one of the most burdensome symptoms for patients with Epidermolysis bullosa (EB), and due to the disease heterogeneity, pain management requires an individualized approach. This meta-analysis identified nine studies of those four topical and one systemic study showed a significant improvement in pain scores. The variety of different tools used for measuring pain underscore the importance to foster harmonisation in patient reported outcomes measurement tools, especially in pain.