Increased MAP-1 and lectin complement activation capacity in Klinefelter syndrome

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Authors

Simon Chang · Aarhus University

Jesper Just · Aarhus University

Anne Skakkebæk · Aarhus University

Emma B Hasselholm · Aarhus University

Christian Nielsen · University of Southern Denmark

Peter Garred · University of Copenhagen

Claus H Gravholt · Aarhus University

Anna-Marie Bloch Münster ·

Abstract

Men with KS demonstrate increased lectin complement pathway activation capacity, increased MAP-1 and MASP1-201 expression. Altered immune function could be a specific characteristic of KS contributing to the comorbidity burden.

Topics & Keywords

Complement system in diseases Systemic Lupus Erythematosus Research Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

Publication Details

Published in: The Journal of Clinical Endocrinology & Metabolism

DOI: 10.1210/clinem/dgag129

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Increased MAP-1 and lectin complement activation capacity in Klinefelter syndrome

Authors

Abstract

Topics & Keywords

Publication Details