Next‐generation Microfluidics for Sustainable Detection Systems

Next-generation microfluidic systems are revolutionizing sustainable detection technologies by integrating miniaturized fluid handling with eco-conscious design. These lab-on-a-chip platforms enable precise, low-volume analysis of biological and environmental samples, offering rapid diagnostics with minimal reagent use and waste. Recent advances focus on biodegradable materials, energy-efficient fabrication, and integration with renewable power sources to reduce environmental impact. Applications span point-of-care diagnostics, environmental monitoring, and food safety, particularly in resource-limited settings. Despite challenges in scalability and regulatory alignment, these systems hold promise for decentralized, low-cost, and sustainable sensing solutions that align with global health and environmental goals. Next-generation microfluidic systems are increasingly leveraging sustainable, high-performance materials to meet the demands of eco-friendly detection platforms. Various materials used for development of next-generation microfluidic systems, viz., paper-based microfluidics for biodegradable and point-of-care diagnostics, cellulose derivatives that offer tunable porosity and surface chemistry for fluid control, and polylactic acid (PLA) for biodegradable 3D-printed microfluidic devices.