Sequencing of Pleural Fluid and Plasma for Tuberculous Pleuritis

20261 citationsJournal Article

Authors

W. K. Jacky Lam · Chinese University of Hong Kong

Ken K. P. Chan · Chinese University of Hong Kong

Guangya Wang · Chinese University of Hong Kong

Christopher K.C. Lai · Chinese University of Hong Kong

Guannan Kang · Chinese University of Hong Kong

Christopher Chan · Chinese University of Hong Kong

Angela C. Y. Leung

Abstract

Targeted sequencing of pleural fluid with selectively masked <i>M. tuberculosis</i> genomic alignment accurately diagnosed TBP and outperformed conventional diagnostic tests. (Supported by InnoHK and the Hong Kong Tuberculosis, Chest and Heart Diseases Association; ClinicalTrials.gov number, NCT05397730.).

Topics & Keywords

Pleural and Pulmonary Diseases Pericarditis and Cardiac Tamponade Tuberculosis Research and Epidemiology

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: NEJM Evidence

Volume 5, Issue 4, pp. EVIDoa2500237-EVIDoa2500237

DOI: 10.1056/evidoa2500237

Field-Weighted Citation Impact: 37.54