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Introduction: Simulation is an evidence-based educational strategy that improves clinical knowledge, skill retention, and team performance—especially for high-risk, low-frequency events (INACSL, 2021; Young et al., 2015). At Froedtert Hospital, cardiopulmonary event reviews revealed delays in defibrillation and communication failures during emergencies. In Q4 2021, only 50% of patients with ventricular fibrillation or pulseless ventricular tachycardia (VF/pVT) received defibrillation within two minutes, falling short of national goals. We hypothesized that a structured, simulation-based education initiative would strengthen team performance, boost confidence, and improve patient outcomes. Methods: An interdisciplinary nurse-led Resuscitation Committee launched three simulation education tracks: 1. In-situ mock codes (Jan 2022–present) in inpatient and ambulatory areas provided real-time, on-unit emergency practice. 2. Formal simulations (Apr 2022–Jun 2023) held in the Simulation Center focused on ACLS algorithms, defibrillation timing, communication, and equipment use. 3. Specialty simulations addressed emerging needs: the Airway Response Team simulation (Mar 2024) targeted peri-intubation teamwork, while the PALS review supported pediatric emergency response. All sessions included a structured pre-brief, active simulation, guided debriefing, and anonymous participant evaluations. Abstract wording was refined with AI assistance and approved by the authors, who retain full responsibility for accuracy. Results: Simulation was highly effective. Participants consistently reported increased knowledge, confidence, and improved communication. In formal simulations, 100% agreed training was critical to job success; 98% called it a worthwhile investment. In the ART simulation, 81% reported better role clarity, and 69% felt more confident speaking up. Following implementation, VF/pVT defibrillation within two minutes rose to 100% by mid-2023. Conclusions: Simulation offers a powerful and scalable approach to improving emergency response. Repeated, immersive practice in a psychologically safe setting enhances rapid assessment, teamwork, and communication. Incorporating simulation into onboarding and professional development can drive sustained improvements in preparedness, patient safety, and clinical outcomes.