Ambulatory Blood Pressure Patterns and Left Ventricular Mass Index in Tanzanian Adults Living with and without HIV

Of the 999 participants enrolled, 959 (96.0%) had at least one complete ABPM measurement (483 PWH/476 PWoH). Office BP was higher in PWoH compared to PWH but nocturnal BPs were similar. Nocturnal dipping percentages were lower in PWH. The prevalence of diastolic non-dipping was 41% in PWH compared to 28% in PWoH (incidence rate ratio 1.42 [1.20,1.69]). Differences in dipping patterns and discrepancies between office and ABPM were apparent in time series analysis. Asleep systolic BP was independently associated with LVMI even after adjusting for office systolic BP in PWH, but not in PWoH. PWH had less nocturnal dipping than PWoH and asleep BP was independently associated with higher LVMI in PWH only. These findings suggest that office BP might underestimate the true BP-related CVD risk in PWH.