Masking effect in the Spanish spontaneous reporting database FEDRA

20260 citationsJournal Articlegold Open Access

Authors

N. Sols Cueto · Agencia Española de Medicamentos y Productos Sanitarios

M.M. Gutiérrez-Lobón · Agencia Española de Medicamentos y Productos Sanitarios

A. Núñez Ventura · Agencia Española de Medicamentos y Productos Sanitarios

C. Fernández-Fernández · Agencia Española de Medicamentos y Productos Sanitarios

Abstract

Purpose: This study aimed to analyse the potential masking effect of drug-event combinations (DECs) with extreme reporting rates and to evaluate the impact on disproportionality analysis and therefore in signal detection. Methods: An algorithm is prop

Topics & Keywords

Pharmacovigilance and Adverse Drug Reactions Advanced Causal Inference Techniques Deception detection and forensic psychology

UN Sustainable Development Goals

Good health and well-being

Publication Details

DOI: 10.22541/au.177434319.98636726/v1

Field-Weighted Citation Impact: 0.00