Effects of photobiomodulation on oral mucositis, oral pain, xerostomia, salivary flow rate, and quality of life in patients with head and neck cancer: a systematic review and meta-analysis

Photobiomodulation appears to be a promising supportive care intervention, reducing the risk of severe mucositis and oral pain, while potentially improving salivary flow rates and preserving quality of life in patients with head and neck cancer. However, the certainty of the evidence ranged from very low to low and most included studies presented a high risk of bias; therefore, these findings should be interpreted with caution.