Estimating the sensitivity of non-treponemal and treponemal antibody tests in primary syphilis

20260 citationsJournal Article

Authors

Stephanie Sweitzer · University of North Carolina at Chapel Hill

J Chen · University of North Carolina at Chapel Hill

Mitch Matoga

Liu Yang · Southern Medical University

Eduardo López-Medina · Centro Internacional de Entrenamiento e Investigaciones Medicas

Jonny A. García-Luna · Centro Internacional de Entrenamiento e Investigaciones Medicas

Ilse Hoffman · University of North Carolina at Chapel Hill

Abstract

Among patients with primary syphilis, sensitivity of TRUST was 55% (6/11) compared to darkfield microscopy (DFM) and 60% (9/15) compared to Treponema pallidum PCR. Sensitivity of RPR was 78% (38/49) and 93% (43/46), respectively. TPPA had a sensitivity of 95% (41/43) compared to DFM and 96% (43/45) compared to PCR.

Topics & Keywords

Syphilis Diagnosis and Treatment Reproductive tract infections research Autoimmune and Inflammatory Disorders

Publication Details

Published in: Sexually Transmitted Diseases

DOI: 10.1097/olq.0000000000002297

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Estimating the sensitivity of non-treponemal and treponemal antibody tests in primary syphilis

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Abstract

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Publication Details