Quantitative Assessment of Kidney Interstitial Fibrosis Using an Intrarenal Optical Spectroscopy

Intrarenal ESS provides a robust, depth-resolved, and quantitative estimation of fibrosis that closely parallels histological IFTA scoring. Multi-depth sampling improves predictive accuracy by minimizing local variability. ESS represents an objective, rapid adjunct for point-of-care tissue evaluation at multiple sites within the kidney, without the need for a biopsy or inflicting any complications.