[Use of NSAIDs in inflammatory bowel disease].

Health Technology Assessment (HTA) Region Stockholm conducted a systematic review evaluating the risk of flare-ups from use of non-steroidal anti-inflammatory drugs (NSAID) in patients with inflammatory bowel disease (IBD). Patients with IBD, such as ulcerative colitis and Crohn's disease, often experience pain including joint pain, pain from kidney stones, menstrual pain, and headache. Effective pain management is crucial for maintaining daily function and quality of life. There are concerns that NSAIDs may increase the risk of IBD flare-ups, and international guidelines vary in their recommendations. The overview indicates that short-term NSAID use is likely associated with a minimal or negligible increase in risk among patients with well-controlled IBD in remission. The findings are however uncertain due to limited data and methodological limitations in the included studies.