WCN26-4345 PREDICTIVE MODELING OF FLUID VOLUMES TO SUPPORT FLUID MANAGEMENT IN HEMODIALYSIS PATIENTS: A RETROSPECTIVE ANALYSIS OF THE MONITORING DIALYSIS OUTCOMES (MONDO) DATABASE

Optimized fluid management is key to improving outcomes in dialysis patients, as extracellular water (ECW) overload is associated with adverse outcomes. Comorbidities and subclinical chronic inflammation, both highly prevalent in this population, can result in loss of muscle mass, reflected by a decrease in intracellular water (ICW). Estimates of total body water (TBW) are essential for quantifying and scaling the dialysis dose and thus for assessing dialysis adequacy in individual patients. The Body Composition Monitor (BCM, Fresenius Medical Care) is a validated, non-invasive tool that estimates fluid volume compartments as TBW, ECW and ICW.