WCN26-2085 ASSOCIATION BETWEEN SYSTEMIC INFLAMMATION AND CHRONIC KIDNEY DISEASE PROGRESSION IN JAPAN: A RETROSPECTIVE COHORT STUDY USING THE J-CKD-DB-EX REGISTRY

Systemic inflammation, a risk factor associated with both the onset and progression of chronic kidney disease (CKD), is commonly defined as a C-reactive protein (CRP) level ≥2 mg/L. This threshold is primarily used in Western populations, whereas Japanese patients generally present with relatively lower CRP levels. It remains unclear if CRP level is associated with CKD progression within these lower ranges. The objective of this study was to evaluate the association between CRP levels and CKD progression in patients with CKD in Japan.