Intraoperative margin assessment using fluorescence confocal microscopy during robot‐assisted radical prostatectomy: a first experience

Intraoperative surgical margin assessment using FCM is feasible and demonstrates good diagnostic accuracy compared with final histopathology, with rapid turnaround times compatible with routine surgical workflows. Diagnostic performance improves when clinically relevant PSM length thresholds are applied. Larger multicentre studies and randomised trials are warranted to determine whether FCM-guided intraoperative decision-making can improve oncological and functional outcomes after RARP.