WCN26-6548 Clinical Risk Factors Associated with In-Hospital Frailty Progression in Patients with Cardiovascular Diseases, Including Hemodialysis

Results: Nationally, in the current (2020), heat waves were responsible for 491,362 (227,772-694,191) stages 4-5 CKD cases (about 30.06% of all cases and 45.31 per 100,000 adults), disproportionately affecting rural areas (PAF: 47.08 per 100,000) and subtropical and tropical regions (PAF: 52.43 per 100,000).The average driving time to the nearest hospital for ACs was 15.8 (7.6-22.3)minutes, with rural areas showing significantly longer times (20.4 minutes) and lower accessibility.The national Gini index for hospital accessibility was 0.45, indicating significant inequality, which was more pronounced in rural areas (0.50), Eastern regions (0.49), and Western regions (0.46).Projections indicated increasing trends in PAFs under high-emission scenarios (e.g., SSP5-8.5 showing >2-fold increase in 2090), while high levels of hospital accessibility inequality could persist across all future climate scenarios.Conclusion: Heat waves induce a substantial and spatially uneven burden of advanced CKD in China, compounded by significant inequalities in hospital accessibility.These inequalities are likely to persist under future climate change given current hospital accessibility settings.I have no potential conflict of interest to disclose.I did not use generative AI and AI-assisted technologies in the writing process.