WCN26-6042 Antigen and Antibody Dual-Target Proximity Extension Assay for Comprehensive Complement System Analysis

20260 citationsJournal Articlegold Open Access

Authors

Haider Cuello Garcia · Jiangsu University

Yue Yan · Viva Biotech (China)

Haitao Liu · Viva Biotech (China)

Hao Zhu · Jiangsu University

Yang Zhou · Jiangsu University

Haifeng Shi · Jiangsu University

Hongxing Shen · Jiangsu University

Abstract

Dysregulated complement activation contributes to glomerular injury in atypical hemolytic uremic syndrome, C3 glomerulopathy, diabetic kidney disease, and other glomerulonephritides. Conventional ELISAs quantify single factors or autoantibodies but are limited by low throughput, labor-intensive workflows, suboptimal specificity, and high sample consumption.

Topics & Keywords

Complement system in diseases Monoclonal and Polyclonal Antibodies Research Blood groups and transfusion

UN Sustainable Development Goals

Decent work and economic growth

Publication Details

Published in: Kidney International Reports

Volume 11, Issue 4, pp. 105692-105692

DOI: 10.1016/j.ekir.2026.105692

Field-Weighted Citation Impact: 0.00