Improving the estimation of population iodine status: A new method for calculating the precision and subgroup differences of median urinary iodine concentration from spot urine specimens

The Box-Cox transformation enables the calculation of results which account for complex sampling, and enables the estimation of the statistical significance of apparent subgroup differences and offers a more accurate approach to analyzing skewed UIC data. Program planners can use this approach to prioritize population groups with insufficient iodine status and tailor nutrition programs to address inequities in iodine nutrition.