WCN26-3515 CHARACTERISTICS OF GENOME-WIDE ASSOCIATION STUDIES OF KIDNEY-RELATED TRAITS IN EAST ASIANS

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Authors

Yuka Sugawara · The University of Tokyo

Yosuke Hirakawa · The University of Tokyo

Akira Narita · Tohoku University

K Ito · RIKEN Center for Integrative Medical Sciences

Hajime Nagasu · Kawasaki Medical School

S. Koshiba · Tohoku University

Shinichi Namba ·

Abstract

Chronic kidney disease (CKD) is a major global health issue, affecting over 10% of adults worldwide and showing high prevalence in East Asia. However, the genetic architecture of CKD and related traits in East Asians has been less explored compared with Europeans. Because genetic associations can be ancestry-specific, studies in non-European populations are crucial for understanding disease biology and ensuring equitable application of genomic discoveries. We therefore investigated kidney-related traits in East Asians through large-scale genome-wide association study (GWAS) meta-analyses and further integrated the results with European data in a trans-ancestry meta-analysis.

Topics & Keywords

Genetic Associations and Epidemiology Chronic Kidney Disease and Diabetes Race, Genetics, and Society

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Kidney International Reports

Volume 11, Issue 4, pp. 105102-105102

DOI: 10.1016/j.ekir.2026.105102

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