WCN26-8785 Bone-Heart Axis in Mild Chronic Kidney Disease–Mineral and Bone Disorder: Phosphate Metabolism and Tissue-Specific Remodeling

In a prior CKD S1-5 cohort (N=1,213; 48% male; age 48±16 years), echocardiographic features of left ventricular hypertrophy were independently associated with serum phosphate (Pi). To elucidate mechanisms linking Pi dysregulation to cardiovascular remodeling in mild CKD-MBD, we conducted translational study.