WCN26-8395 PREVALENCE OF VITAMIN D DEFICIENCY AND INSUFFICIENCY IN FILIPINO PATIENTS WITH CHRONIC KIDNEY DISEASE ON HEMODIALYSIS: A HOSPITAL-BASED CROSS-SECTIONAL STUDY

Results: Among the 1,434 patients included (median age 68 years, median eGFR 25mL/min/1.73m2,35% women), 386 (27%) discontinued RAS inhibitors over a median follow-up of 35 months.The 3-year adjusted relative risk of MACE associated to discontinuing RAS inhibitors, compared to continuing, was 2.02 (95% CI, 1.62 to 2.47), and that of KRT initiation, 1.34 (95% CI, 1.14 to 1.60). Conclusion:RAS inhibitor discontinuation was strongly associated with MACE and KRT risks, the leading causes of morbidity and mortality in advanced CKD.Our results, along with other published data, suggest that the risk-benefit balance favors continued use of RAS inhibitors in this population.I have no potential conflict of interest to disclose.I did not use generative AI and AI-assisted technologies in the writing process.