WCN26-644 MECHANISM AND CLINICAL SIGNIFICANCE OF VITAMIN B6 DEFICIENCY IN CHRONIC KIDNEY DISEASE

Vitamin B6 (B6) is a coenzyme essential for collagen cross-linking in bone and for regulating cytokine synthesis. Although B6 deficiency has been frequently reported in chronic kidney disease (CKD), its mechanism remains unclear. We re-evaluated our previously unassessed data from studies on B-vitamin metabolism in CKD to investigate the potential mechanisms of B6 deficiency.