Muscle Weakness and the Irisin–BDNF and Oxidative Stress Axis in the 60‐Day Pseudorandomised Controlled AGBRESA Bed Rest Study

AG exposure attenuated some of the BR-induced changes in twitch contractile properties. Neither BR nor AG induced significant alterations in systemic oxidative stress, or muscle protein carbonylation, suggesting that the main contribution to the BR-induced loss of muscle strength during the AGBRESA study was not oxidative stress.