WCN26-4542 Clinicopathological Features of Obesity-Related Glomerulopathy: A Multicentre Case Series of Biopsy-Proven Cases Validated by Proposed Diagnostic Criteria

low kidney function.RI evaluation in the clinical course of parvovirus B19 induced GN is thus far not reported.Methods: A male in his sixties was hospitalized due to fever, rash, and edema.He was diagnosed with parvovirus B19 induced GN complicated with AKI because of family history, blood and urine analysis such as hypocomplementemia, IgM type anti-parvovirus B19 antibody, proteinuria, and hematuria.Doppler echographic renal examination was performed on the 2nd and 17th day of hospitalization.Serial change of RI was considered combined with clinical parameters.Results: Serum creatinine level was 4.2 mg/dl prior to hospitalization and 3.8 mg/dl on the day of admission, which implies his kidney function already began to improve when hospitalized.On the 3rd day, however, he showed dyspnea on effort, body weight gain, and hypoxemia with elevation of brain natriuretic peptide (BNP) concentration and pulmonary congestion on thoracic X-ray examination.Echocardiography showed normal wall motion and no dilation of ventricles but inferior vena cava was enlarged.To treat his overhydration diuretics were initiated.During several days his symptoms resolved with decrease in body weight and BNP.On the 2nd day RI was 0.8 and fractional excretion of Na (FENa) was 0.1 %.On the 17th day RI was 0.6 and FENa was 0.8 %.Kidney size evaluated by ultrasonography decreased and body weight reduced by 9 kg through 17 days with eGFR recovered.Proteinuria and hematuria disappeared.At the outpatient clinic follow-up 2 weeks after discharge, hypocomplementemia was not seen.