Plasma Proteins Associated With Psychosocial Factors and Heart Disease: The Jackson Heart Study

20260 citationsJournal Article

Authors

Sara O’Brien · University of North Carolina at Chapel Hill

Madeline G Gillman · University of North Carolina at Chapel Hill

Michael D. Green · Duke University

Daniel E. Cruz · Beth Israel Deaconess Medical Center

James S. Floyd · University of Washington Tacoma

Susan Hankinson · University of Massachusetts Amherst

Daniel H. Katz

Abstract

Novel associations between psychosocial factors, plasma proteins, and cardiovascular disease were identified in JHS. Circulating proteomic profiles across 3 cardiovascular disease cohorts showed differences in protein concentrations by psychosocial measures. Future investigations should identify additional potentially targetable proteomic mechanisms by which psychosocial factors contribute to disease.

Topics & Keywords

Cardiac Health and Mental Health Stress Responses and Cortisol Heart rate and cardiovascular health

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Arteriosclerosis Thrombosis and Vascular Biology

DOI: 10.1161/atvbaha.125.324125

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