Impact of 5‐ASA discontinuation in children with ulcerative colitis on biologic therapy: A propensity score‐matched study

20260 citationsJournal Articlehybrid Open Access

Authors

Giulia D'Arcangelo · Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Luca Scarallo · Meyer Children's Hospital

Giulia Mancuso · Sapienza University of Rome

Mara Corpino · Ospedale Microcitemico

Claudio Romano · University of Messina

L. Norsa · Ospedale Papa Giovanni XXIII

Serena Arrigo

Abstract

5-ASA discontinuation might negatively impact the clinical course of children with UC treated with anti-TNF. Considering the good safety profile of the drug, continuing mesalamine can be suggested as a prudent approach.

Topics & Keywords

Inflammatory Bowel Disease Inflammatory mediators and NSAID effects Gastroesophageal reflux and treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Pediatric Gastroenterology and Nutrition

DOI: 10.1002/jpn3.70415

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