Platelet‐Activating Factor Pathway in Women With Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity

20260 citationsJournal Articlehybrid Open Access

Authors

Joan Duran‐Bertran · Hospital Universitari Joan XXIII de Tarragona

Helena Clavero‐Mestres · Institut de Recerca Biomèdica Catalunya Sud

Razieh Mahmoudian · Institut de Recerca Biomèdica Catalunya Sud

Sara Muñiz‐Piera · Institut de Recerca Biomèdica Catalunya Sud

Carmen Aguilar · Institut de Recerca Biomèdica Catalunya Sud

David Riesco · Hospital Universitari Joan XXIII de Tarragona

Abstract

The PAF-PAFR axis is upregulated in obesity-associated MASLD and is strongly linked to inflammatory and injury-related histological features, supporting PAFR as a potential therapeutic target. Conversely, plasma Lp-PLA2 does not appear to be a reliable noninvasive biomarker of MASLD severity in women with obesity.

Topics & Keywords

Liver Disease Diagnosis and Treatment Adipokines, Inflammation, and Metabolic Diseases Liver Disease and Transplantation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Obesity

DOI: 10.1002/oby.70178

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