Staying on track: collagen fibers orientation strongly affects thrombi formation at high shear

20260 citationsJournal Article

Authors

Е.А. Melnikova · Center for Theoretical Problems of Physicochemical Pharmacology

Dmitry Yu. Nechipurenko · Center for Theoretical Problems of Physicochemical Pharmacology

Mikhail A Panteleev · Center for Theoretical Problems of Physicochemical Pharmacology

Abstract

Type III lengthwise collagen fibers are the ones promoting platelet translocation and stable adhesion at high shear rates, which may be relevant for triggering thrombus formation in vivo.

Topics & Keywords

Platelet Disorders and Treatments Blood properties and coagulation Protease and Inhibitor Mechanisms

Publication Details

Published in: Thrombosis and Haemostasis

DOI: 10.1055/a-2841-9953

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Staying on track: collagen fibers orientation strongly affects thrombi formation at high shear

Authors

Abstract

Topics & Keywords

Publication Details