Sex differences in chemotherapy-induced neuropathic pain: mechanisms and pharmacotherapy

20260 citationsJournal Article

Authors

Xinyi Wu · Ningbo University

Litao Chen · Ningbo University

Yu Chen · Ningbo University

Yixin Liu · Ningbo University

Xin Chen · Ningbo University

Abstract

Sex is a crucial biological variable in CIPN, influencing drug efficacy through sex-specific neuroimmune mechanisms and hormonal regulation. These findings underscore the necessity of incorporating sex as a key variable in analgesic development and clinical practice to achieve personalized pain management in CIPN patients.

Topics & Keywords

Pain Mechanisms and Treatments Cancer Treatment and Pharmacology Pain Management and Opioid Use

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Pharmacy and Pharmacology

Volume 78, Issue 3

DOI: 10.1093/jpp/rgag025

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