Endoplasmic reticulum stress-related genes drive M1 macrophage polarization in preeclampsia via modulating metabolic reprogramming: a bioinformatic study

20260 citationsJournal Articlediamond Open Access

Authors

Chunzi Xu · Nantong University

Ruikun Hu · Nantong University

Yue Lu · Nantong University

Ling Gu · Nantong University

Hui Xu · Nantong University

Xu Huang · Nantong University

Abstract

HTRA1, GBA1, KL, and PC may serve as diagnostic biomarkers for PE, potentially influencing M1 polarization of placental macrophages via metabolic reprogramming.

Topics & Keywords

Pregnancy and preeclampsia studies Neonatal and fetal brain pathology Birth, Development, and Health

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: Hypertension in Pregnancy

Volume 45, Issue 1, pp. 2649740-2649740

DOI: 10.1080/10641955.2026.2649740

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