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Background. Intermittent photic stimulation (IPS) entails systematic variation of stroboscopic light frequency and may provoke a photoparoxysmal response (PPR) in susceptible individuals. Objectives. To improve the diagnostic yield in patients with suspected idiopathic generalized epilepsy and a high probability of juvenile myoclonic epilepsy (JME) based on clinical history, despite the absence of interictal epileptiform discharges and a negative initial IPS on routine electroencephalography (EEG), thereby facilitating diagnosis and reducing the need for prolonged EEG recordings. Methods. This prospective study included 50 EEG recordings from patients with JME obtained between December 2021 and December 2023. All EEGs were performed using a standardized protocol. PPRs were specifically recorded and analyzed at two time points: during the routine EEG and after completion of the recording. Results. Photoparoxysmal responses (PPRs) were observed in 58% of cases, with sustained responses in 28% and ictal events occurring in 8%. Eighteen patients exhibited PPR during the initial IPS, while an additional 11 patients developed PPR following repeated IPS testing. Significant differences were noted in the timing of photic hypersensitivity, sustained responses, and Waltz classification of PPR; however, no significant differences were observed in age or sex between the PPR-positive and PPR-negative groups. Analysis of the epileptogenic frequencies revealed that PPR was most frequently elicited at 18 Hz in 18 patients (11 during the first IPS and 6 during the second IPS). Conclusion. A photoparoxysmal response (PPR) was most frequently observed at an IPS frequency of 18 Hz. Combining two non-consecutive IPS trials may increase the detection of photosensitivity without clearly increasing ictal events during the second IPS. The PPR duration was longer in the first IPS at 25 Hz and longer in the second IPS at 10 Hz.