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Overview This audit provides a critical cybernetic and epidemiological deconstruction of the Global Plan to End TB 2023-2030. It identifies the current US $249.98B roadmap as a "Success-Only" probabilistic model that remains highly vulnerable to systemic collapse following the progress "amputation" caused by COVID-19. Key Objectives The paper seeks to resolve four critical "Black Boxes" that currently impede global eradication efforts: Human Agency, Infrastructure Fragility, Geopolitical Sovereignty, and Algorithmic Complexity. By moving beyond "hope-based" advocacy, the author proposes a Deterministic Construction framework—treating the end of TB as an engineered certainty rather than a statistical guess. Proposed Technical Solutions Deterministic Filtering: A mandate for a 100% transition from manual microscopy to AI-powered Digital Chest X-ray (CXR) to eliminate the "Subclinical Blind Spot" in asymptomatic carriers. Incentive Logic: Utilizing structural violence mitigation to "lock" diagnoses to immediate, automated mobile financial transfers, transforming patients into system-stakeholders. Rhizomatic Infrastructure: Deployment of satellite-linked, low-power edge-computing nodes to ensure "Relational Saturation" and diagnostic persistence in connectivity-deprived regions. Linear-Time Modeling: Implementation of State Space Models (SSMs)—specifically Mamba-inspired architectures—to allow linear-time processing of massive infection chains on standard mobile hardware. Sovereign Entanglement: The creation of Bilateral Health Bonds and automated smart-contract GERD taxing to align a nation's GDP growth and credit ratings with real-time epidemiological performance. Conclusion The audit concludes with the Omega Mandate: a call to amputate obsolete diagnostic protocols, automate financial support circuits, and entangle sovereign interests into a decentralized TB R&D treasury. Keywords Tuberculosis (TB) Global Plan to End TB Cybernetics Edge Computing State Space Models (SSMs) Public Health Architecture Deterministic Modeling Epidemiology Smart Contracts