Multimodal Approach for Recalcitrant Melasma Using Picosecond Laser and Topical <scp>JAK</scp> Inhibition: A Case Report

This case illustrates the potential clinical value of combining pigment-targeted picosecond laser therapy with topical JAK inhibition and visible light-specific photoprotection for recalcitrant melasma. The durable remission achieved supports further investigation into anti-inflammatory and photoreactive pathway modulation as adjunctive strategies in melasma management.