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<strong class="journal-contentHeaderColor">Abstract.</strong> One potentially scalable method to remove CO<sub>2</sub> from the air is ocean alkalinity enhancement (OAE), which works to lower surface ocean partial pressure (pCO<sub>2</sub>) and accelerate CO<sub>2</sub> sequestration and durable storage. This study explores how OAE might affect the seasonal carbon cycle, which plays a key role in the ocean’s annual CO<sub>2</sub> uptake. By analysing earth system model simulations of OAE implemented continuously at the European coastline until 2100 under low and high climate forcing, it was found that: when carbon cycle seasonality is temperature-driven, a) OAE enhances CO<sub>2</sub> uptake in winter, when it is naturally strongest, and it reduces ocean pCO<sub>2</sub> in summer, when it is naturally highest; b) higher CO<sub>2</sub> emissions increase the sensitivity of the seasonal carbon cycle; c) a region with a shallow bathymetry and well-mixed waters may be ideal for implementing OAE due to fast air-sea CO<sub>2</sub> equilibration.