Electroconvulsive Therapy and the Longitudinal Modulation of Sleep Architecture

20260 citationsJournal Article

Authors

Mohammad Mehdi Kafashan · Heart Rhythm Society

Lucas Lebovitz

Zitian Zhou · Washington University in St. Louis

Subha Subramanian · Beth Israel Deaconess Medical Center

Alyssa K. Labonte · Graduate School USA

Robby Greenspan

Nan Lin · Washington University in St. Louis

Yo-El S Ju

Abstract

Our findings demonstrate that ECT increases N3 sleep and SWA in the responders' group, with SWA changes mediating improvements in depressive symptoms. These findings highlight SWA as a biomarker of antidepressant response and a potential target for sleep-based strategies to augment brain stimulation therapies for depression.

Topics & Keywords

Sleep and Wakefulness Research Sleep and related disorders Electroconvulsive Therapy Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Ect

DOI: 10.1097/yct.0000000000001265

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