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ABSTRACT Objective: This study utilised meta-analysis to investigate the association between type 2 diabetes mellitus and peri-implant diseases (including peri-implantitis and peri-implant mucositis). Methods: Literature databases (PubMed, Web of Science, Cochrane Library, and Embase) were systematically searched, and studies investigating the association between diabetes mellitus and peri-implant diseases were included. The NewcastleOttawa Scale was used to assess the quality of the literature, and pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using either a random-effects or a fixed-effects model. Results: Ten studies involving 2,657 patients with edentulism who received dental implant restorations were included. The prevalence of peri-implantitis ranged from 1.20% to 63.70%, and the prevalence of peri-implant mucositis ranged from 31.00% to 64.60%. Meta-analysis results showed a significant association between diabetes mellitus and an increased risk of peri-implantitis (OR: 2.05; 95% CI: 1.522.77). A potential association between diabetes mellitus and peri-implant mucositis (OR: 1.22; 95% CI: 0.911.63) was observed, but it did not reach statistical significance. Additionally, smoking (OR: 1.99; 95% CI: 1.57-2.52) and periodontitis (OR: 3.99; 95% CI: 1.4411.01) were significant risk factors for peri-implantitis. Conclusion: This study suggests that diabetes mellitus is associated with an increased risk of peri-implant diseases, particularly peri-implant inflammation. Future higher-quality studies are still needed to investigate further the impact of diabetes mellitus and dynamic glycaemic control on peri-implant diseases.