Beyond Standard Culture: Diagnostic Value of Ureaplasma and Chlamydia in Women with UTI Symptoms

Atypical pathogens are prevalent and frequently underdiagnosed causes of lower urinary tract symptoms in women with negative standard urine cultures. Integrating molecular and specialized culture methods substantially enhances diagnostic accuracy and enables targeted therapy. Tetracyclines and macrolides appear to be the most appropriate empirical treatment options in settings with a high prevalence of <i>U. urealyticum</i>.