Analysis and validation of mast cells and enriched genes in colorectal cancer with liver metastasis by multi-omics data

20260 citationsJournal Articlegold Open Access

Authors

Zhao-yi Wei · First Affiliated Hospital of GuangXi Medical University

Liang Hao · First Affiliated Hospital of GuangXi Medical University

Jian-wen Li · First Affiliated Hospital of GuangXi Medical University

Feng Lv · Guangxi Medical University

Bang-li Hu · Guangxi Medical University

Jinxin Liu · First Affiliated Hospital of GuangXi Medical University

Abstract

Low proportion of activated MCs is associated with liver metastasis in CRC. The model constructed using three MC-enriched genes could effectively predict CRC patients with liver metastasis and their survival outcomes.

Topics & Keywords

Mast cells and histamine Ferroptosis and cancer prognosis Connective Tissue Growth Factor Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Discover Oncology

DOI: 10.1007/s12672-026-04916-2

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