Therapeutic potential of interleukin-33 blockade in mitigating synovial inflammation and cartilage damage

20260 citationsJournal Article

Authors

Yan Feng · Liaoning Vocational College of Medical

S Wu · Liaoning Vocational College of Medical

Y Jiang · Liaoning Vocational College of Medical

X Liu · Liaoning Vocational College of Medical

Abstract

IL-33 blockade effectively mitigates synovial inflammation and joint destruction by suppressing the proliferation, migration, and invasion of RA-FLSs while promoting their apoptosis. Targeting IL-33 may represent a promising strategy for the treatment of rheumatoid arthritis.

Topics & Keywords

IL-33, ST2, and ILC Pathways Eosinophilic Esophagitis Autoimmune and Inflammatory Disorders Research

Publication Details

Published in: Scandinavian Journal of Rheumatology

DOI: 10.1080/03009742.2026.2640725

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Therapeutic potential of interleukin-33 blockade in mitigating synovial inflammation and cartilage damage

Authors

Abstract

Topics & Keywords

Publication Details