Associations of corticosteroid therapy with weight change and appetite in patients with advanced pancreatic cancer – a post hoc analysis from the MISTRAL trial

In long-term follow-up, corticosteroid treatment was associated with greater weight loss and poorer appetite among patients with advanced pancreatic cancer. These findings may partly be explained by a higher symptom burden among patients receiving corticosteroids. Future prospective trials are warranted to clarify the effect of long-term corticosteroid treatment on weight and appetite.