Cystatin B Attenuates Cerebral Ischemia Reperfusion Injury by Inhibiting the <scp>JAK2</scp> / <scp>STAT3</scp> Signaling Pathway

This study identifies CSTB as a novel negative regulator of CIRI. Its protective role is mediated through the inhibition of apoptosis and inflammatory responses via the JAK2/STAT3 axis, suggesting its potential as a therapeutic target for ischemic stroke.