PATHOPHYSIOLOGICAL CHANGES IN THE LIVER DURING ACUTE INFLAMMATION

This review highlights the pathophysiological changes that occur in the liver during acute inflammation, based on a systematic analysis of scientific research and literature. The article examines microcirculatory disturbances, hepatocyte injury mechanisms, cytokine and inflammatory mediator imbalances, oxidative stress, and the role of the antioxidant system. Findings from both domestic and international studies underscore the importance of understanding liver injury and functional disturbances, monitoring these changes, and developing effective therapeutic strategies. The review provides theoretical and practical insights for clinical practice and further research.