Raw Pharmacological Data (qPCR, ELISA, Flow Cytometry, Colorimetric Assays) from Murine Metabolic and Inflammatory Studies

The dataset contains raw pharmacological data generated from experiments performed on murine blood and tissue samples. These data were obtained to quantify metabolic parameters and inflammatory biomarkers using a combination of molecular, immunological and biochemical techniques. No human subjects are involved, and the dataset does not contain personal or sensitive information. The biological material includes whole blood, plasma, serum, and tissue homogenates, depending on the assay. Each sample is identified through coded alphanumeric identifiers that do not reveal animal facility information or experimental group names directly. 1) Bioquimica-Elisa-qPCR-citometria: data generated to quantify metabolic parameters and inflammatory biomarkers using molecular, immunological, and cytometric techniques of molecules BP2 and THQ5a after administration to obese mouse model (ob/ob). No human data are included.Dataset associated with the publications: Villarroel-Vicente C et al. Bioorg Chem 2025, 160, 108450. doi: 10.1016/j.bioorg.2025.108450, for THQ5aMarques P et al. Pharmacol Res 2023, 187, 106638. doi: 10.1016/j.phrs.2022.106638, for BP2 2) ELISA-qPCR_THP-1: data generated to quantify inflammatory citoquines using ELIS and qPCR techniques of THQ5a on THP-1 cells.Dataset associated with the publication: Villarroel-Vicente C et al. Bioorg Chem 2025, 160, 108450. doi: 10.1016/j.bioorg.2025.108450, for THQ5a