High-Level Alzheimer Disease Neuropathological Change Following Iatrogenic Exposure

20260 citationsJournal Articlehybrid Open Access

Authors

Gargi Banerjee · MRC Prion Unit

Tze How Mok · MRC Prion Unit

Harpreet Hyare · National Hospital for Neurology and Neurosurgery

Oliver Cousins · St George’s University Hospitals NHS Foundation Trust

Zane Jaunmuktane · NIHR Queen Square Dementia Biomedical Research Unit

Simon Mead · MRC Prion Unit

John Collinge

Abstract

These results demonstrate that patients with iAD can have histopathological findings classically found in sporadic AD and that prominent language involvement might be an important phenotypic feature in this AD subtype.

Topics & Keywords

Dementia and Cognitive Impairment Research Parkinson's Disease Mechanisms and Treatments Genetic Neurodegenerative Diseases

UN Sustainable Development Goals

Quality Education

Publication Details

Published in: JAMA Neurology

DOI: 10.1001/jamaneurol.2026.0437

Field-Weighted Citation Impact: 0.00