Neonatal Diabetes Case Series in Myanmar: Early Presentation of Lifelong Condition

Neonatal Diabetes Mellitus (NDM) is a rare form of monogenic diabetes that presents within the first six months of life, characterized by persistent hyperglycaemia due to impaired insulin secretion resulting from genetic defects that affecting pancreatic beta cell function. It may be transient or permanent depending on the underlying mutation1. Early recognition and appropriate therapy is essential to prevent crucial mortality and morbidity. In resource limited setting management of NDM poses significant challenging due to limited access to genetic testing, continuous glucose monitoring. The diabetes technology supports the comprehensive and successful management of NDM. At Yangon Children's Hospital (YCH), ten cases of NDM were reported and managed between 2014 and 2024. Initial management primarily involved insulin infusion, subcut- aneous insulin therapy, frequent glucose monitoring, and careful nutritional support to prevent hypoglycaemia. Parental education, close patient follow up are critical component