An unrecognized non-pathologic filling defect on hysterosalpingography: A case report

Background: Despite advancements in medical technology, hysterosalpingography (HSG) remains one of the most commonly used diagnostic tools in the evaluation of infertile women. Filling defects are a common abnormal finding in this technique and can be attributed to both pathological causes, such as polyps and submucosal fibroids, or nonpathological factors, such as air bubbles and mucus plaques. In this study, we used imaging techniques including HSG and saline-infused sonography. Case Presentation: Here, we discuss a rare normal variation in HSG of a 35-yr-old woman with primary infertility, no history of underlying disease or surgery, that appears as filling defects for which no underlying cause can be found upon further investigation. Conclusion: Familiarity with this diverse range of filling defects helps radiologists avoid misdiagnoses and unnecessary follow-up imaging.