<scp>RRM2</scp> Promotes the Progression of Intrahepatic Cholangiocarcinoma by Inhibiting Ferroptosis Through the <scp>HIF</scp> ‐1α Pathway

20260 citationsJournal Articlehybrid Open Access

Authors

Yinghui Song · Hunan Normal University

Yufeng Li · Hunan Normal University

Jia Zhou · Hunan Normal University

You Peng · Hunan Normal University

Guoyi Xia · The Central Hospital of Shaoyang

X. W. Chen · Hunan Normal University

Yi Jiang ·

Abstract

RRM2 inhibited ferroptosis by regulating the HIF-1α signalling pathway, thereby promoting the progression of ICC. The RRM2/HIF-1α/ferroptosis axis may become a potential target for ICC therapy.

Topics & Keywords

Cholangiocarcinoma and Gallbladder Cancer Studies Ferroptosis and cancer prognosis Cancer, Hypoxia, and Metabolism

Publication Details

Published in: Liver International

Volume 46, Issue 5, pp. e70623-e70623

DOI: 10.1111/liv.70623

Field-Weighted Citation Impact: 0.00

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<scp>RRM2</scp> Promotes the Progression of Intrahepatic Cholangiocarcinoma by Inhibiting Ferroptosis Through the <scp>HIF</scp> ‐1α Pathway

Authors

Abstract

Topics & Keywords

Publication Details