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Background. The increasing prevalence of orthodontic pathologies among the population leads to a growing need for orthodontic treatment, which is prolonged, complex, and multi-stage. An important component of successful orthodontic treatment is the psycho-emotional state of patients. Treatment with fixed orthodontic appliances is effective, but certain stages are accompanied by pronounced pain syndrome, which negatively affects the quality of life of patients and requires additional correction to achieve treatment success. Aim. To conduct a comparative assessment of the psycho-emotional state of orthodontic patients undergoing treatment with fixed orthodontic appliances (braces). Materials and methods of the study. A total of 60 orthodontic patients undergoing treatment with fixed appliances (braces) were examined. To assess their psycho-emotional state, the following tools were used: the State-Trait Anxiety Inventory (STAI) by C. D. Spielberger, adapted by Yu. L. Khanin; the Corah’s Dental Anxiety Scale (DAS); and the Pain Catastrophizing Scale (PCS). Numerical data were processed using Microsoft Excel 2019 with the XLSTAT and Analyse-it plugins and utilities. Results. According to Corah’s DAS scale, 31 patients (51.7%) of all those examined demonstrated a high level of anxiety; 14 patients (23.3%) each presented with a moderate level of anxiety and pronounced dental phobia (panic fear); 1 patient (1.7%) had a total score of 4–8 points, which corresponded to a low level of anxiety and a calm attitude. Among women, a state of high anxiety prevailed in 54.5%, pronounced dental phobia (panic fear) in 24.2%, and a moderate level of anxiety in 21.3%; indicators corresponding to a low level of anxiety and a calm attitude were not diagnosed among women. Among men, a high level of anxiety also prevailed in 48.2%, a moderate level in 25.9%, and pronounced dentophobia (panic fear) in 22.2%; a low level of anxiety and a calm attitude were characteristic of 1 man (3.7% of the total number of men). In orthodontic patients with different levels of personal anxiety, the distribution of PCS scores varied. Among women with high and moderate personal anxiety, the rumination state prevailed (30.2% and 12.1% of the total number of women examined, respectively). The magnification (exaggeration) state was noted in 24.2% and 6.1% of the total number of women examined; it is characterized by clinically significant catastrophizing that requires clinical intervention. Among men with high personal anxiety, the rumination state also prevailed (37.1% of the total number of men surveyed). Among men with moderate anxiety, the helplessness state prevailed (14.8% of the total number of men surveyed). The magnification state, characterized by clinically significant catastrophizing, was observed in 14.8% of men with high personal anxiety and 3.7% of men with moderate personal anxiety. Conclusions. Among the criteria for the success of orthodontic treatment is the patient’s psychological profile, which necessitates studying motivational factors and personal characteristics that may determine the perception of one’s appearance and readiness for long-term treatment. Among the examined orthodontic patients, the largest group (63.3%) was characterized by a high level of personal anxiety.