<scp> <i>UGT1A1</i> </scp> Fragment Analysis: Genotyping the ( <scp>TA</scp> ) <sub>n</sub> Variable Repeat Polymorphism for Clinical Applications

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Authors

Ryan N. Baugher · Frederick National Laboratory for Cancer Research

Kristen Pike · Frederick National Laboratory for Cancer Research

Teri M. Plona · Frederick National Laboratory for Cancer Research

Stephanie D. Mellott · Frederick National Laboratory for Cancer Research

Todd B. Young · Frederick National Laboratory for Cancer Research

Heidi E. Lawhorn · Frederick National Laboratory for Cancer Research

Abstract

Clinical implementation as a supplemental assay to other pharmacogenomics offerings resulted in a correction rate of the loci within patient samples of 7.8%, with 2.77% caused by miscalling UGT1A1*37 variant.

Topics & Keywords

Pharmacogenetics and Drug Metabolism Blood disorders and treatments Genomics and Rare Diseases

Publication Details

Published in: Journal of Clinical Laboratory Analysis

DOI: 10.1002/jcla.70214

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<scp> <i>UGT1A1</i> </scp> Fragment Analysis: Genotyping the ( <scp>TA</scp> ) <sub>n</sub> Variable Repeat Polymorphism for Clinical Applications

Authors

Abstract

Topics & Keywords

Publication Details