A H3K27me3 reader complex couples H3K27me3 accumulation to nascent transcription of transposable elements in Paramecium

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Authors

Thomas Balan · Centre National de la Recherche Scientifique

Ambre Petitalot · Centre National de la Recherche Scientifique

Julien Richard Albert · Centre National de la Recherche Scientifique

Louise Abbou · Centre National de la Recherche Scientifique

Guillaume Chevreux · Centre National de la Recherche Scientifique

Bassem Al-Sady · University of California, San Francisco

Abstract

This positive feedback loop to enrich H3K27me3 at TEs is analogous to self-reinforcing loops leading to H3K9 methylation at repeats in fungi, plants and animals. Our work reveals a unique association between H3K27me3 readers and active transcription.

Topics & Keywords

Protist diversity and phylogeny Chromosomal and Genetic Variations Developmental Biology and Gene Regulation

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: Genome biology

DOI: 10.1186/s13059-026-04045-7

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