Altered neutrophil signalling linked to impaired chemotaxis and increased ROS and NET production in older people with frailty

This work provides novel insight into the altered neutrophil phenotype associated with ageing in good health and ageing with frailty, and highlights similarities between inflammageing in frailty and chronic inflammation in RA. This may be important in the development of therapeutics and/or health management strategies to support healthy living as we age.